SulindacSulindac (clinoril) is a nonsteroidal anti-inflammatory drug (NSAID) that is used for treating pain, fever, and inflammation.
Sulindac lowers the levels of prostaglandins, chemicals that are produced by the body and are partly responsible for pain,
fever, and inflammation. Sulindac blocks prostaglandin enzyme (cyclooxygenase), resulting in lower concentrations
of prostaglandins. As a consequence, inflammation, pain and fever are reduced.
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|Sulindac 150mg (genric Clinoril)
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SULINDAC MEDICATION INFO
The following information is intended as a supplement, but not as a substitution for the expertise and judgment of
your doctor, pharmacist or other healthcare professional. It should not be assumed that use of the drug is safe,
appropriate, or effective for your condition. Consult your healthcare professional before using this drug.
Sulindac rarely can result in serious (sometimes fatal) bleeding from the stomach and/or intestines. This effect can occur without
warning symptoms at any time while taking this drug. The elderly may be at higher risk for this effect. (See also Precautions and
Drug Interactions sections.)
SULINDAC - ORAL (SUL-in-dak)
COMMON BRAND NAME(S): Clinoril
Sulindac results in the reduction of pain, swelling, and joint stiffness from arthritis. It is also used to treat arthritis of the spine,
gouty arthritis, and shoulder bursitis/tendonitis. Sulindac is known as a nonsteroidal anti-inflammatory drug (NSAID).
If you are treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other
medications to treat your pain. Note - also see the "Warning" section of this page.
Read the Medication Guide provided by your pharmacist before you start using Sulindac and each time you get a refill. If you have any questions,
ask your doctor or pharmacist.
Consume this med by mouth as directed by your doctor, usually twice daily. Take Sulindacn with a full glass of water (8 ounces),
unless your doctor directs you otherwise. Do not lie down for the remainder of 10 minutes after taking Sulindac. Take Sulindac either with food, right after
meals, or with antacids to prevent stomach upset.
To reduce side effect risks (such as stomach bleeding), use Sulindac at the
lowest effective dose for the shortest possible length of time. Do not increase your dose or take it more often than prescribed. For chronic conditions
such as arthritis, continue taking it as directed by your doctor. Discuss the risks and benefits with your doctor or pharmacist. Also, the manufacturer
recommends that you do not take more than 400 milligrams per day because this may increase your risk of liver problems.
In certain conditions (such as arthritis), 1-2 weeks may be required before the full benefits take effect when Sulindac is taken regularly.
If you are taking Sulindac on an "as needed" basis (not on a regular schedule), remember that pain medications work best if they are used as the
first signs of pain occur. If you wait until the pain has significantly worsened, the medicine may not work as well.
Contact your doctor if your condition worsens.
SIDE EFFECTS: See Warning section also.
Upset stomach, nausea, vomiting, gas, diarrhea, constipation, dizziness, or headache may occur. If any of these side effects persist or worsen, contact your doctor or pharmacist promptly.
Remember that your doctor has prescribed Sulindac because he or she has judged that the benefit to you is greater than the risk of side effects.
Many people using this medication do not have serious side effects.
Contact your doctor right away if any of these unlikely but serious side effects occur: swelling of the hands or feet (edema), sudden or unexplained
weight gain, hearing changes (such as ringing in the ears), mental/mood changes, difficult/painful swallowing, unusual tiredness.
Get medical help right away if any of these rare but very serious side effects occur: change in the amount of urine, unexplained stiff neck.
In rare cases, Sulindac cause serious (possibly fatal) liver disease. If you notice any of the following highly unlikely but very serious side effects,
stop taking sulindac and contact your doctor immediately: dark urine, persistent nausea/vomiting, severe stomach/abdominal pain, yellowing eyes or skin.
A very serious allergic reaction to Sulindac is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction,
including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
See also Warning section.
Before taking Sulindac, tell your doctor or pharmacist if you are allergic to it; or to aspirin or other NSAIDs (such as ibuprofen, naproxen,
celecoxib); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Talk to your doctor for more details.
Before using Sulindac, tell your doctor or pharmacist your medical history, especially of: asthma (including a history of worsening breathing
after taking aspirin or other NSAIDs), bleeding or clotting problems, growths in the nose (nasal polyps), heart disease (such as previous heart attack),
high blood pressure, kidney stones, liver disease, stomach/intestinal/esophagus problems (such as bleeding, ulcers, recurring heartburn), stroke.
Kidney problems can sometimes occur with the use of NSAID medications, including Sulindac. Problems are more likely to occur if you are dehydrated,
have heart failure or kidney disease, are an older adult, or if you take certain medications (see also Drug Interactions section). Drink plenty of
fluids as directed by your doctor to prevent dehydration and contact your doctor right away if you have any unusual change in the amount of urine.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).
Sulindac may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely.
Sulindac may cause stomach bleeding. Daily use of alcohol and tobacco, especially when combined with this medicine, may increase your risk for
stomach bleeding. Limit alcohol and stop smoking. Consult your doctor or pharmacist for more information.
Sulindac may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths or sunlamps. Use a sunscreen and wear protective clothing when outdoors.
Older adults may be more sensitive to the side effects of Sulindac, especially stomach bleeding and kidney problems.
Before using Sulindac, women of childbearing age should talk with their doctor(s) about the benefits and risks (such as miscarriage). Tell your
doctor if you are pregnant or if you plan to become pregnant. During pregnancy, Sulindac should be used only when clearly needed. It is not
recommended for use during the first and last trimesters of pregnancy due to possible harm to the unborn baby and interference with normal labor/delivery.
It is unknown if Sulindac passes into breast milk. Breast-feeding while using Sulindac is not recommended. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This website
does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal
products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with Sulindac include: aliskiren, ACE inhibitors (such as captopril, lisinopril), angiotensin II receptor blockers
(such as losartan, valsartan), cidofovir, dimethyl sulfoxide (DMSO), cyclosporine, lithium, methotrexate, pemetrexed, corticosteroids (such as prednisone).
Sulindac may increase the risk of bleeding when taken with other drugs that also may cause bleeding. Examples include anti-platelet drugs
such as clopidogrel, "blood thinners" such as dabigatran/enoxaparin/warfarin, among others.
Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (aspirin, NSAIDs
such as celecoxib, ibuprofen, or ketorolac). These drugs are similar to sulindac and may increase your risk of side effects if taken together.
However, if your doctor has directed you to take low-dose aspirin to prevent heart attack or stroke (usually at dosages of 81-325 milligrams a day),
you should continue taking the aspirin unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details.
OVERDOSE: If overdose is suspected,
contact your local poison control center or emergency room immediately.
Symptoms of overdose may include severe stomach pain, coffee ground-like
vomit, dark stool, ringing in the ears, change in amount of urine,
unusually fast or slow heartbeat, muscle weakness, slow or shallow
breathing, confusion, severe headache or loss of consciousness.
NOTES: Do not share Sulindac
with others. Laboratory and/or medical tests may be performed to
monitor your progress.
MISSED DOSE: If you miss a dose of Sulindac,
use it as soon as you remember. If it is near the time of the next
dose, skip the missed dose and resume your usual dosing schedule.
Do not "double-up" the dose to catch up.
STORAGE: Store Sulindac at room temperature
between 59 and 86 degrees F (15 - 30 degrees C) away from light
and moisture. Do not store Sulindac in the bath room.