MaxaltMaxalt (also known as Rizatriptan) is a headache medicine that narrows the blood vessels surrounding the brain. Maxalt also reduces substances in the body
that can trigger headache pain, nausea, light and sound sensitivity, and additional migraine symptoms.
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|Rizatriptan (generic Maxalt) 5mg
|Rizatriptan (generic Maxalt) 10mg
|Rizatriptan (generic Maxalt) ODT 5mg
|Rizatriptan (generic Maxalt) ODT 10mg
|Maxalt 5mg (brand)
|Maxalt 5mg (brand)
|Maxalt 10mg (brand)
|Maxalt 10mg (brand)
The following information is intended as a supplement, but not as a substitution for the expertise and judgment of
your physician, pharmacist or other healthcare professional. It should not be assumed that use of the drug is safe,
appropriate, or effective for your particular condition. Consult your healthcare professional before using this drug.
You should not take Maxalt if you have a known allergy to rizatriptan, if you have any history of heart disease, or if you have coronary
heart disease, angina, blood circulation problems, lack of blood supply to the heart, high blood pressure that does not stay in check, ischemic
bowel disease, a history of cardiac ingfraction or stroke, or if your headache seems to be different from your usual migraine headaches.
Do not take Maxalt within 24 hours before or after using another migraine headache medicine, including almotriptan (Axert),
eletriptan (Relpax), naratriptan (Amerge), sumatriptan (Imitrex), zolmitriptan (Zomig), or ergot
medicine such as ergotamine (Ergomar or Migergot), dihydroergotamine (D.H.E., Migranal), or methylergonovine (Methergine).
Avoid using Maxalt if you have taken a monoamine oxidase inhibitor (MAOI) such as furazolidone (Furoxone), isocarboxazid (Marplan),
phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), or Parnate in the last 14 days.
Before using Maxalt, tell your doctor if you have liver or kidney disease, blood pressure that has not been controlled, a heart rhythm disorder, or
coronary heart disease (or risk factors such as diabetes, menopause, smoking, being overweight, having high cholesterol, having a
family history of coronary artery disease, being a male over 40, or being a woman who has undergone a hysterectomy).
Tell your doctor if you are also taking an antidepressant such as citalopram - Celexa, duloxetine - Cymbalta, escitalopram - Lexapro, fluoxetine - Prozac or Sarafem, fluvoxamine - Luvox, paroxetine (Paxil, Pexeva), sertraline (Zoloft), trazodone
(Desyrel, Oleptro) or venlafaxine (Effexor).
Maxalt will only treat a headache that is already ocurring and will not prevent future headaches or reduce the number of attacks.
After taking a Maxalt tablet, you must wait 2 hours before consuming another tablet. Avoid taking more than 30 mg of Maxalt (rizatriptan) in 24 hours.
RIZATRIPTAN - ORAL
(RYE za TRIP tan)
COMMON NAME: Maxalt
USAGE: Maxalt (Rizatriptan) is used in the treatment of migraines. It helps to relieve headache, pain, and other migraine symptoms (including nausea,
vomiting, sensitivity to light/sound). Prompt treatment helps you return to your normal routine and may decrease your need for other pain
medications. Maxalt (Rizatriptan) belongs to a class of drugs known as triptans. It affects a certain natural substance (serotonin) that causes
narrowing of blood vessels in the brain. It may also relieve pain by affecting certain nerves in the brain.
Maxalt (Rizatriptan) does not prevent future migraines or lessen how often you get migraine attacks.
HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start taking rizatriptan and
each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take Maxalt orally or as directed by your doctor, at the first sign of a migraine. It may be taken with or without food, but
may work faster when it is taken on an empty stomach. The dosage is based on your medical condition, age, response to treatment, and
other drugs you may be taking. For children, the dosage is also based on weight. Be sure to tell your doctor and pharmacist about all
the products you use (including prescription drugs, nonprescription drugs, and herbal products).
If there is no improvement in your symptoms, do not take more doses of Maxalt (Rizatriptan) before talking to your doctor. If your symptoms
are only partly relieved, or if your headache comes back, adults may take another dose at least 2 hours after the first dose. For adults, the
US manufacturer recommends a maximum dose of 30 milligrams in a 24-hour period.
Overuse of drugs to treat sudden migraine attacks can sometimes worsen a headache (also known as medication overuse headache) or rebound headache.
Therefore, do not use Maxalt (Rizatriptan) more often or for longer than prescribed. Tell your doctor if you need to use Maxalt (Rizatriptan) more often,
if Maxalt (Rizatriptan) is not working as well, or if you have more frequent or worse headaches. Your doctor may need to change your medication and/or
add another medication to help prevent headaches.
SIDE EFFECTS: Flushing, feelings of tingling/numbness/prickling/heat, tiredness, weakness, drowsiness, or dizziness may occur. If any of these
effects persist or worsen, tell your doctor immediately.
Remember that your doctor has prescribed Maxalt (Rizatriptan) because he or she has judged that the benefit to you is greater than the risk of side effects.
Many people using Maxalt (Rizatriptan) do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: blue fingers/toes/nails, cold hands/feet, hearing changes, mental/mood changes.
Tightness in the jaw or neck can occur soon after using Maxalt (Rizatriptan). Only rarely are these signs of a serious condition. However, you may not be
able to tell it apart from a serious reaction due to a lack of blood flow to the heart, brain, or other parts of the body. Get medical help right away
if you have any very serious side effects, including: chest pain, jaw/left arm pain, fainting, fast or pounding heartbeat, vision changes,
weakness on one side of the body, confusion, slurred speech, sudden or severe stomach/abdominal pain, bloody diarrhea, change in the amount of urine.
Maxalt (Rizatriptan) may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also
taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get medical help
right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea,
twitching muscles, unexplained fever, unusual agitation/restlessness.
A very serious allergic reaction to Maxalt (Rizatriptan) is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction,
including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible Rizatriptan side effects. If you notice other effects not listed above, contact your doctor immediately.
PRECAUTIONS: Before using Maxalt (Rizatriptan), tell your doctor if you are allergic to it; or if you have any other allergies. Maxalt (Rizatriptan) may
contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your doctor for more details.
Before using Maxalt (Rizatriptan), tell your doctor or pharmacist your medical history, especially of: blood circulation problems (for example, in your legs,
arms/hands, or stomach), certain types of headaches (hemiplegic or basilar migraine), heart problems (such as chest pain, irregular heartbeat, previous
heart attack), liver disease, seizure, stroke or "mini-stroke" (transient ischemic attack).
Certain conditions can increase your risk for heart problems. Tell your doctor if you have any of these conditions, including: high blood pressure, high
cholesterol, diabetes, family history of heart disease, overweight, or smoking status.
Maxalt (Rizatriptan) may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such
activities safely. Avoid alcoholic beverages.
The risk of heart disease, liver disease, and high blood pressure increases with age. Older adults may be more sensitive to the side effects of Maxalt (Rizatriptan),
especially increased blood pressure and heart problems.
If you are pregmant, Maxalt should be utilized only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding while using Maxalt (Rizatriptan).
DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This website does
not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products)
and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Taking MAO inhibitors with Maxalt (Rizatriptan) may cause a serious (possibly fatal) drug interaction. Avoid consuming any MAO inhibitors (isocarboxazid,
linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) during treatment with Maxalt (Rizatriptan).
Most MAO inhibitors should also not be taken for two weeks before treatment with Maxalt (Rizatriptan). Ask your doctor when to start or stop taking
Serotonin syndrome/toxicity is a risk that increases if you are also taking other drugs that create excess serotonin in the brain. Examples include street drugs such
as MDMA/"ecstasy," St. John's wort, certain antidepressants (including SSRIs such as fluoxetine/paroxetine, SNRIs such as duloxetine/venlafaxine),
among others. The risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs.
If you also take any ergotamine medication (such as dihydroergotamine or methysergide) or other "triptan" drugs (such as sumatriptan, zolmitriptan),
you will need to separate your rizatriptan dose at least 24 hours apart from your dose of these other medications to lessen the chance of serious side effects.
OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222.