EvistaEVISTA® (raloxifene HCl) is a prescription medication approved for the prevention and treatment of osteoporosis in women after menopause.
EVISTA DRUG INFO
Why is this medication prescribed?
Raloxifene is used to prevent and treat osteoporosis, a disease common in women past menopause, which results in bones that break easily. Raloxifene is in a class of medications called selective estrogen receptor modulators (SERMs). It works by acting similar to estrogen, a female hormone produced by the body. Like estrogen, raloxifene increases the density of bone.
How should I take Evista?
Take Evista exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
Raloxifene can be taken with or without the addition of food or beverage.
Take Evista at the same time each day.
Your doctor may want you to take calcium and vitamin D supplements if you do not receive enough of these substances from your regular diet.
Weight-bearing and lifting exercises may also be helpful, as they are known to strengthen bone over an extended period of time.
Store raloxifene at room temperature away from moisture and heat.
Other uses for this medicine
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information. There is interest in possible beneficial effects of raloxifene on breast cancer risk in women.
What special precautions should I follow?
Before taking raloxifene,
What special dietary instructions should I follow while taking Evista?
- tell your doctor and pharmacist if you experience an allergic reaction to raloxifene or any other drugs.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin), cholestyramine (Questran) or colestipol (Colestid), diazepam (Valium, Valrelease, Zetran), diazoxide (Proglycem), and estrogen or hormone replacement therapy (ERT or HRT). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you have cancer and if you have or have ever had breast lumps or cancer, high blood cholesterol or triglycerides, blood clots (e.g., in the legs, lung, or eye), phlebitis in the leg, heart failure, or liver disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking raloxifene, call your doctor immediately. Raloxifene may harm the fetus.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking raloxifene.
- you should know that raloxifene increases the risk of blood clots. Because being inactive also increases the risk of blood clots, you should stop taking raloxifene 72 hours before a long period of lying down (for example, when recovering from surgery or when on bedrest). Resume taking raloxifene once you become active again. During long trips, make sure to get up and walk around every once in a while.
- you should know that raloxifene has not been found to cause spotting or menstrual-like bleeding nor to increase the risk of cancer of the uterine lining. However, tell your doctor if you develop unexplained vaginal bleeding or spotting.
- you should know that raloxifene has not been found to cause breast tenderness or swelling nor to increase the risk of breast cancer. However, tell your doctor if you notice any changes or palpable alterations in your breasts.
Follow all dietary and exercise recommendations, including those regarding calcium and vitamin D supplements.
What should I do if I forget a dose?
Take the missed dose of Evista as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Raloxifene may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- hot flashes (more common in the first 6 months of raloxifene therapy)
- leg cramps
- swelling of the hands, feet, ankles, or lower legs
Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:
What storage conditions are needed for this medicine?
- sudden chest pain or chest heaviness
- difficulty breathing or coughing up blood
- pain, swelling, or warmth in the calves, legs, hands, or feet
- sudden change in your vision such as vision loss or blurring
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control
center at 1-800-222-1222. If the victim has collapsed
or is not breathing, call local emergency services at
What other information should I know about Evista?
Keep all appointments with your doctor and the laboratory. You should have a complete physical examination, including blood pressure measurements, breast and pelvic exams, and a Pap test at least yearly. Follow your doctor's directions for examining your breasts; report any lumps immediately. Your doctor may order certain lab tests to check your body's response to raloxifene.
Before you have any laboratory tests, tell the person doing the test that you take raloxifene, as this medication may interfere with some lab tests.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.