CIPRO DRUG INFO
IMPORTANT NOTE: The
following information is only intended to supplement, not substitute
for, the expertise and judgment of your doctor, pharmacist or
other healthcare professional. It should not be construed to indicate
that use of the drug is safe, appropriate, or effective for you.
Consult your healthcare professional before using this drug.
CIPROFLOXACIN - ORAL (SIP roe FLOX a sin)
COMMON BRAND NAME(S): Cipro
What are the uses?: Cipro is used to treat a variety of bacterial infections. Ciprofloxacin belongs
to a class of drugs called quinolone antibiotics. It works by stopping the growth of bacteria.
Cipro treats only bacterial infections. It will not work for virus infections (such as
common cold, flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.
How do I use this medicine?: Read the Medication Guide and, if available, the Patient Information Leaflet
provided by your pharmacist before you start taking ciprofloxacin and each time you get a refill.
If you have any questions, ask your doctor or pharmacist.
Take Cipro by mouth with or without food as directed by your doctor, usually twice a day in the morning and evening.
The tablet may have a bitter taste if you split, chew, or crush it before taking it. The
manufacturer recommends swallowing the tablet whole for this reason.
The dosage and length of treatment is based on your medical condition and response to treatment.
Drink plenty of fluids while taking this medication unless your doctor tells you otherwise.
Take Cipro at least 2 hours before or 6 hours after taking other products that may bind
to it, decreasing its effectiveness. Ask your pharmacist about the other products you take. Some
examples include: quinapril, sucralfate, vitamins/minerals (including iron and zinc supplements),
and products containing magnesium, aluminum, or calcium (such as antacids, didanosine solution, calcium supplements).
Calcium-rich foods, including dairy products (such as milk, yogurt) or calcium-enriched juice, can
also decrease the effect of this medication. Take this medication at least 2 hours before or 6 hours
after eating calcium-rich foods, unless you are eating these foods as part of a larger meal that
contains other (non-calcium-rich) foods. These other foods decrease the calcium binding effect.
Ask your doctor or pharmacist about safely using nutritional supplements/replacements with Cipro.
Antibiotics work best when the amount of medicine in your body is kept at a constant level.
Therefore, take Cipro at evenly spaced intervals.
Continue to take Cipro until the full prescribed amount is finished, even if symptoms
disappear after a few days. Stopping the medication too early may result in a return of the infection.
What are the side effects?: Nausea, diarrhea, dizziness, lightheadedness, headache, and trouble sleeping may occur.
If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed Cipro because he or she has judged that the benefit to
you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Cipro may rarely cause serious nerve problems that may be reversible if identified and treated
early. Get medical help right away if you develop any of the following symptoms: pain/numbness/burning/tingling/weakness
in any part of the body, changes in how you sense touch/pain/temperature/body position/vibration.
Tell your doctor right away if you experience any serious side effects, including: skin that sunburns more easily
(also known as sun sensitivity), unusual bruising/bleeding, signals of a new infection (such as new/persistent fever,
persistent sore throat), unusual change in the amount of urine you pass, change in color of urine (red/pink urine),
signs of liver problems (such as unusual tiredness, stomach/abdominal pain, persistent nausea or vomiting,
yellowing eyes/skin, dark urine).
Medical help should be sought right away if you experience any of the following: severe/persistent headache,
vision changes, shaking (tremors), seizures, severe dizziness, fainting, fast/irregular heartbeat, mental/mood
changes (such as anxiety, confusion, hallucinations, depression, rare thoughts of suicide).
Cipro may rarely cause a significant intestinal condition (Clostridium difficile-associated diarrhea)
due to a type of bacteria that has become resistant. This condition may occur during treatment or weeks to months after
treatment has stopped. Let your doctor know right away if you develop: persistent diarrhea, abdominal or stomach
pain/cramping, blood/mucus in your stool.
Do not use anti-diarrhea products or narcotic pain medications if you have any of these symptoms because
these products may make them worse.
Use of Cipro for prolonged or repeated periods may result in oral thrush or a new yeast infection.
Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms.
A very serious allergic reaction to Cipro is rare. However, get medical help right away if you notice any
symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat),
severe dizziness, trouble breathing.
What precautions should I take?: Before taking Cipro, tell your doctor or pharmacist if you are allergic to it; or to other
quinolone antibiotics such as norfloxacin, gemifloxacin, levofloxacin, moxifloxacin, or ofloxacin; or if you have any other
allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Talk to your pharmacist for more details.
Before using Cipro, tell your physician or pharmacist your medical history, especially of: diabetes, heart
problems (such as recent heart attack), joint/tendon problems (such as tendonitis, bursitis), disease of the kidney or liver,
myasthenia gravis, nervous system disorders (such as peripheral neuropathy), seizures, conditions that increase
your risk of seizures (such as brain/head injury, brain tumors, cerebral atherosclerosis).
Cipro may result in heart rhythm issue (QT prolongation). QT prolongation can infrequently
result in serious (rarely fatal) fast/irregular heartbeat and other symptoms (such as severe dizziness, fainting)
that need medical attention right away.
The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may
cause QT prolongation. Before using Cipro, tell your doctor or pharmacist of all the drugs you take and if you
have any of the following conditions: certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG),
family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death).
Low levels of potassium or magnesium in the blood may also increase your risk of QT prolongation. This risk may increase
if you use certain drugs (such as diuretics/"water pills") or if you have conditions such as severe sweating, diarrhea,
or vomiting. Talk to your doctor about using Cipro safely.
Cipro may rarely cause serious changes in blood sugar levels, especially if you have already been diagnose with diabetes. Watch for symptoms
of high blood sugar including increased thirst and urination. Cipro may increase the blood sugar-lowering effects
of the medication glyburide. Also watch for symptoms of low blood sugar such as sudden sweating, shaking, fast heartbeat,
hunger, blurred vision, dizziness, or tingling hands/feet. Check your blood sugar regularly as directed by your doctor and
report any changes. If you experience symptoms of low blood sugar, you may raise your blood sugar by using glucose tablets/gel
or eating a quick source of sugar such as straight sugar, honey, or candy, or drinking fruit juice or non-diet soda. Tell your
doctor immediately about the reaction and the use of this product. To help prevent low blood sugar, eat meals on a regular
schedule, and do not skip meals. Your doctor may need to switch you to another antibiotic or adjust your diabetes medications
if any reaction occurs.
Cipro has the potential to cause dizziness. Do not drive, use machinery, or do any activity that requires alertness until you are sure you
can perform such activities safely. Limit alcoholic beverages.
Cipro may make you more sensitive to the sun. Avoid prolonged sun exposure, tanning booths, and sunlamps. Use a
sunscreen and wear protective clothing when outdoors. Other medications (such as tretinoin-mequinol) may increase your sun
sensitivity. Ask your doctor or pharmacist for more details.
Cipro may cause live bacterial vaccines (such as typhoid vaccine) not to work as well. Therefore, do not have any
immunizations/vaccinations while using this medication without the consent of your doctor.
Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription
drugs, and herbal products).
Young adults and children may be more sensitive to the side effects of Cipro, especially joint/tendon problems.
Older adults may be more sensitive to the side effects of this drug, especially tendon problems (especially if they are also
taking corticosteroids such as prednisone or hydrocortisone) and QT prolongation (see above).
During pregnancy, Cipro should be used only when clearly needed. Discuss the risks and benefits with your doctor.
Cipro passes into breast milk. Consult your doctor before breast-feeding.
Are there any warnings?: Cipro may rarely cause tendon damage (such as tendonitis, tendon rupture) during or after treatment.
Your risk for tendon problems is greater if you are over 60 years of age, if you are taking corticosteroids
(such as prednisone), or if you have a kidney, heart, or lung transplant. Stop exercising, rest, and get medical
help right away if you develop joint and/ormuscle pain or swelling.
Cipro should not be used by patients with myasthenia gravis. It may cause the condition to become worse.
Get medical help right away if you develop muscle weakness or trouble breathing.
What drug interactions are there?: Drug interactions may change how your medications work or increase your risk for serious side effects.
This website does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products)
and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Some products that may interact with Cipro include: "blood thinners" (such as acenocoumarol, warfarin), strontium.
Many drugs besides Cipro may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide,
quinidine, procainamide, sotalol, among many others.
It is important to note that Cipro can slow down the processing of other medications within the body, which may affect how they work.
Examples of affected drugs include duloxetine, pirfenidone, tizanidine, among others.
Avoid drinking large amounts of beverages containing caffeine (coffee, tea, colas), eating large amounts of chocolate,
or taking over-the-counter products that contain caffeine. Cipro may increase and/or prolong the effects of caffeine.
Although most antibiotics probably do not affect hormonal birth control such as pills, patch, or ring, some antibiotics
have the potential to decrease their effectiveness. This could cause pregnancy. Examples include rifamycins such as rifampin or rifabutin.
Be sure to ask your doctor or pharmacist if you should use additional reliable birth control methods while using this antibiotic.
What if there's an overdoe?: If overdose is suspected,
contact your local poison control center or emergency room immediately.
Additional Information: Do not share Cipro with other people.
Cipro has been prescribed for your current condition only. Do not use Cipro
later for another infection unless your doctor directs you to do so. A different antibiotic may be necessary in that case.
Laboratory and/or medical tests (such as kidney function, blood counts, cultures) should be performed periodically to monitor your
progress or to check for side effects. Consult your doctor for more details.
Do not change brands of Cipro without checking with your doctor or pharmacist. Not all brands have the same effects.
MISSED DOSE: If you miss a dose of Cipro, take it as soon as you remember. If it is near the time of the next dose,
skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.
STORAGE: Store Cipro at room temperature away from light and moisture. Do not store Cipro the bathroom. Keep all medications away from children and pets.