The following information is intended to supplement, not substitute
for, the expertise and judgment of your physician, pharmacist
or other healthcare professional. It should not be construed
to indicate that use of the drug is safe, appropriate, or
effective for you. Consult your healthcare professional before
using this drug.
BUPROPION - ORAL (byou-PRO-pee-on)
COMMON BRAND NAME(S): Wellbutrin
USES: This medication is
used to treat depression.
HOW TO USE BUPROPION:
Take bupropion exactly as it was prescribed for you. Do not take it in larger doses or for longer than recommended by your doctor. Your doctor may occasionally change your dose to make sure you get the best results from the medication.
Bupropion can be taken with or without food.
Take each dose with a full glass of water.
Do not crush, chew, or break the extended-release tablet (Wellbutrin SR, Wellbutrin XL, Zyban SR). Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.
If you take Zyban to help you stop smoking, you may continue to smoke for about 1 week after you start the medicine. Set a date to quit smoking during the second week of Zyban treatment. By that time you will have enough of the medicine in your blood stream to help you quit smoking. Talk to your doctor if you are having trouble quitting after you have used Zyban for at least 7 weeks.
Your doctor may prescribe nicotine patches or gum to help support your smoking cessation treatment. Be sure you read all directions and safety information for the nicotine product. Using nicotine with Zyban may raise your blood pressure and your doctor may want to check your blood pressure regularly. Do not smoke at any time if you are using a nicotine product along with Zyban. Too much nicotine can cause serious side effects.
Do not stop taking bupropion without first talking to your doctor. You may have unpleasant side effects if you stop taking this medication suddenly.
If you use the bupropion extended-release tablet, the tablet shell may pass into your stools (bowel movements). This is normal and does not mean that you are not receiving enough of the medicine.
Store bupropion at room temperature away from moisture and heat.
SIDE EFFECTS: Bupropion
is generally well tolerated. Dry mouth, headache, increased
sweating, nausea/vomiting, constipation, anxiety, fatigue
and blurred vision may occur. If these effects persist or
worsen, notify your doctor. Report promptly: unusual weight
loss or gain, palpitations, agitation, trouble sleeping. Unlikely
but report promptly: tremor, dizziness, fainting, mood changes,
slowed movements, difficulty urinating, decreased sex drive,
drowsiness. Very unlikely but report promptly: seizures, mental
problems, fever, muscle aches, yellowing of the eyes or skin.
In the unlikely event you have an allergic reaction to this
drug, seek medical attention immediately. Symptoms may include
trouble breathing, rash, itching, swelling, or severe dizziness.
If you notice other effects not listed above, contact your
doctor or pharmacist.
PRECAUTIONS: Before taking
bupropion, tell your doctor if you have: history of seizures
or head injury or brain tumor, heart disease, liver or kidney
disease, eating disorder, diabetes, alcohol dependence, any
allergies, the intent to quit smoking. Because of the possibility
this drug will make you dizzy and affect coordination, do
not drive or operate machinery until you get used to the drug's
effects. Limit or avoid consumption of alcoholic beverages;
alcohol can increase your risk of seizures. Chronic alcohol
users who suddenly stop the intake of alcohol while taking
bupropion may increase the risk of having seizures. Suddenly
stopping certain tranquilizers (e.g., diazepam, chlordiazepoxide)
is not recommended because doing so may increase the risk
of having seizures. Elderly patients may be more sensitive
to the effects of this drug. Tell your doctor if you are pregnant
or plan to become pregnant before taking this drug. This drug
passes into breast milk. Because of the potential risk to
the infant, breast-feeding while using this drug is not recommended.
Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Before
taking bupropion tell your doctor of all nonprescription and
prescription medications you may use especially: MAO inhibitors
(e.g., isocarboxazid, phenelzine, tranylcypromine, pargyline,
selegiline, linezolid, furazolidone), levodopa, ritonavir,
corticosteroids (e.g. prednisone), sedatives, adrenaline-like
stimulants (e.g., ephedrine), products containing nicotine
(e.g., patches or gum). Also report use of drugs which might
increase seizure risk (decrease seizure threshold) such as:
phenothiazines (e.g., chlorpromazine), tricyclic antidepressants
(e.g., amitriptyline), isoniazid (INH), theophylline. Excess
caffeine intake can increase the chance of seizures with this
drug. Check all nonprescription/prescription drug labels for
caffeine. Consult your doctor or pharmacist. A certain product
used to help quit smoking contains bupropion. Do not take
that product while using this one. Do not start or stop any
medicine without doctor or pharmacist approval.
OVERDOSE: If overdose of Bupropion is
suspected, contact your local poison control center or emergency
room immediately. Symptoms of overdose may include seizures,
hallucinations, rapid heart rate, and loss of consciousness.
NOTES: Do not allow anyone
else to take your Bupropion.
MISSED DOSE: Take any missed
dose as soon as possible but not if it is within 4 hours of
the next dose. If it is time for the next dose, skip the missed
dose and resume your regular schedule. Do not "double-up"
STORAGE: Store at room temperature
and keep away from moisture and sunlight. Do not store in
BUPROPION DRUG INFO