AxertAxert (also known as Almotriptan) is used in the treatment of migraines. It helps to relieve headaches, pain and other symptoms associated with migraines,
including sensitivity to light/sound, nausea, and vomiting. Prompt treatment allows you to get back to your normal routine and may decrease your
need for other pain medications. Axert does not prevent future migraines or reduce the frequency of headaches.
Axert belongs to a group of meds called triptans. It affects a specific natural chemical (serotonin) which constricts blood vessels in the brain.
Axert may also block other pain pathways in the brain.
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AXERT DRUG INFO
The following information is intended as a supplement, but not as a substitution for the expertise and judgment of
your doctor, pharmacist or other healthcare professional. It should not be assumed that use of the drug is safe,
appropriate, or effective for your condition. Consult your healthcare professional before using this drug.
ALMOTRIPTAN - ORAL (AL-moe-TRIP-tan)
COMMON BRAND NAME(S): Axert
USES: Axert (almotriptan) is frequently use in the treatment of migraines. It helps to relieve headaches, pain and other symptoms of migraines, including sensitivity to
light, nausea, and vomiting. Quick treatment allows you to get back to your normal routine and may decrease your need for other pain
medications. Axert (almotriptan) does not prevent future migraines or reduce how often you may get a headache.
Axert (almotriptan) belongs to a group of drugs called triptans. It affects a certain natural chemical (serotonin) that constricts blood vessels
in the brain. Axert (almotriptan) may also block other pain pathways in the brain.
HOW TO USE: Read the Patient Information Leaflet available from your pharmacist before you start using Axert (almotriptan) and each time you
get a refill. Ask your doctor or pharmacist if you have any questions.
Consume Axert (almotriptan) by mouth at the first sign of a migraine, or as directed by your physician. It may be taken with or without food. Do not take
Axert (almotriptan) to prevent a migraine. If there is no improvement in your symptoms, do not take any more doses of Axert (almotriptan) before talking to your doctor.
If your symptoms are only partly relieved, or if the headaces return, you may take a second dose after 2 hours or as directed by your doctor.
Do not take more than 2 doses in a 24-hour period.
If you have never taken Axert (almotriptan) previously and heart disease may be a risk factor for you (observe Precautions), you may be advised to take your first
dose in your doctor's office in order to monitor for rare but serious heart problems (e.g., heart attack).
Your dosage is based on your medical condition and response to therapy. Tell your doctor if your condition does not improve or if it worsens.
Overuse of drugs to treat sudden migraine attacks can lead to worsening of headache (medication overuse headache) or rebound headache. Therefore,
do not use Axert (almotriptan) more often or for longer than prescribed. Tell your doctor if you need to use Axert (almotriptan) more often, if the medication
is not working as well, or if you have more frequent or worse headaches. Your doctor may need to change your medication and/or add a separate medication
to help prevent the headaches.
SIDE EFFECTS: Drowsiness, dizziness, nausea, sensations of tingling/numbness/prickling, or dry mouth may occur. If any of these effects persist or worsen,
notify your doctor.
Remember that your doctor has prescribed Axert (almotriptan) because he or she has judged that the benefit to you is greater than the risk of side effects. Many people
using Axert (almotriptan) do not have serious side effects.
Tightness in the neck or jaw can occur shortly after using Axert (almotriptan). Only rarely are these indications of a condition. However, you may not be able to tell
this apart from a serious reaction related to a lack of blood flow to the heart, brain or other parts of the body. Seek immediate medical attention if any of these
unlikely but very serious (rarely fatal) side effects occur: chest pain, jaw/left arm pain, fainting, fast/irregular/pounding heartbeat, vision changes, weakness on
one side of the body, confusion, slurred speech, sudden or severe stomach/abdominal pain, bloody diarrhea, change in the amount of urine.
Tell your doctor immediately if any of these unlikely but serious side effects occur: blue fingers and/or nails, cold sensation of hands/feet, hearing changes, mental/mood changes.
Axert (almotriptan) may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other
drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get medical help right away if you develop
some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained
fever, unusual agitation/restlessness.
In the unlikely event you have a serious allergic reaction to Axert (almotriptan), seek immediate medical attention. Symptoms of a serious allergic reaction include: rash,
itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a comprehensive list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Before taking Axert (almotriptan), tell your doctor or pharmacist if you are allergic to it; or to other triptan migraine drugs; or if you have any other allergies.
Axert (almotriptan) may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Axert (almotriptan) should not be taken if you have certain medical conditions. Before using Axert (almotriptan), consult your doctor or pharmacist if you have a history of:
heart disease (e.g., chest pain, heart attack), decreased blood flow in the brain (e.g., stroke, transient ischemic attack), blood circulation disease (e.g., ischemic
bowel disease), uncontrolled high blood pressure (hypertension), certain types of headaches (hemiplegic or basilar migraine).
Before using Axert (almotriptan), tell your doctor or pharmacist your medical history, especially of: certain blood circulation disorders (e.g., Raynaud's disease), kidney
problems, liver problems.
Tell your doctor if you have the following risk factors for heart disease: diabetes, family history of heart disease, high blood pressure (controlled), high cholesterol,
overweight, smoker, female after menopause, male over age 40.
If you are at high risk for heart disease, your doctor may want to check your heart before prescribing Axert (almotriptan).
Axert (almotriptan) may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely.
Limit alcoholic beverages.
Axert (almotriptan) should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.
It is not known whether Axert (almotriptan) passes into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects.
This website does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription
drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Other medications can affect the removal of Axert (almotriptan) from your body, which may affect how Axert (almotriptan) works. Examples include azole antifungals
such as ketoconazole/itraconazole, macrolide antibiotics such as erythromycin, protease inhibitors such as ritonavir.
The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotonin. Examples include street drugs such
as MDMA/"ecstasy," St. John's wort, certain antidepressants (including SSRIs such as fluoxetine/paroxetine, SNRIs such as duloxetine/venlafaxine),
among others. The risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs.
If you also take any ergotamine medication (e.g., dihydroergotamine or methysergide) or any other "triptan" drugs (e.g., zolmitriptan, sumatriptan),
you will need to separate your Axert (almotriptan) dose from your dose of these other medications in order to lessen the chance of serious side effects.
Ask you doctor how long you should wait between your doses of these drugs.
Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure
drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine),
psychiatric medicines (e.g., amitriptyline, chlorpromazine, risperidone, trazodone).
Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist
about the safe use of those products.
OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222.
NOTES: Do not share this medication with others.
Take Axert (almotriptan) only as needed when a migraine occurs or as directed by your physician. Axert (almotriptan) should not be taken on a regular schedule.
Never increase your dose of Axert (almotriptan) or take it more often than prescribed by your doctor.
Certain foods/beverages or food additives (e.g., red wine, cheese, chocolate, monosodium glutamate) as well as some lifestyle patterns (e.g.,
irregular eating/sleeping habits, stress) may bring about a migraine headache. Avoiding these "triggers" may help decrease the frequency of
migraine headaches. Consult your doctor for more details.
Laboratory and/or medical tests (such as blood pressure) may be performed periodically to monitor your progress or check for side effects.
Consult your doctor for more details.
MISSED DOSE: Not applicable. (See How to Use section.)