AMERGE DRUG INFO
This is a summary and does NOT include a comprehensive list possible information about Amerge. This information does not assure that Amerge is safe,
effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health
care professional. Always ask your health care professional for complete information about this product and your specific health needs.
NARATRIPTAN - ORAL (nair-uh-TRIP-tan)
COMMON BRAND NAME(S): Amerge
USES: Amerge (Naratriptan) is primarily utilized in the treatment of migraines. It helps to relieve headaches, pain and other symptoms of migraines, including sensitivity to
light/sound, nausea, and vomiting. Prompt treatment allows you to get back to your normal routine and may decrease your need for other pain
medications. Amerge (Naratriptan) does not prevent future migraines or reduce how often you may get a headache.
Amerge (Naratriptan) belongs to the triptan group of medications. It affects a certain natural chemical (serotonin) that constricts blood vessels
in the brain. Amerge (Naratriptan) may also block other pain pathways in the brain.
HOW TO USE:
Read the Patient Information Leaflet available from your pharmacist before you start using Amerge (Naratriptan) and each time you get a refill.
Ask your doctor or pharmacist if you have any questions.
Take one tablet by mouth with or without food, at the first sign of a migraine, or as directed by your doctor. Do not take Amerge (Naratriptan) to
prevent a migraine. If there is no improvement in your symptoms, do not take any more doses of Amerge (Naratriptan) before talking to your doctor.
If your symptoms are only partly relieved, or if your headache comes back, you may take a second dose after 4 hours or as directed by your
doctor. Do not take more than 5 milligrams in a 24-hour period.
If you have never taken Amerge (Naratriptan) before and you have risk factors for heart disease (see Precautions), you may be advised to take your
first dose in your doctor's office in order to monitor for rare but serious heart problems (e.g., heart attack).
Your condition and side effects to therapy will dictate the dosage. Inform your doctor if your condition does not improve or if it worsens.
Overuse of drugs to treat sudden migraine attacks can lead to a worse headache (also known as medication overuse) or rebound headache.
Therefore, do not use Amerge (Naratriptan) more often or for longer than prescribed. Tell your doctor if you need to use Amerge (Naratriptan) more
often, if Amerge (Naratriptan) is not working as well as anticipated, or if you have more frequent or worse headaches. Your doctor may need to change your medication
and/or add a separate medication to help prevent the headaches.
SIDE EFFECTS: Tingling/numbness/prickling/heat, the feeling of flushness, weakness, drowsiness, or dizziness may occur. If any of these
effects persist or worsen, notify your doctor or pharmacist promptly.
Remember that your doctor has prescribed Amerge (Naratriptan) because he or she has judged that the benefit to you is greater than the risk of side effects.
Many people using Amerge (Naratriptan) do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: blue fingers/toes/nails, cold sensation of hands/feet, hearing changes,
Chest/jaw/neck tightness can commonly occur shortly after using naratriptan. Only rarely are these signs of a serious condition. However, you may
not be able to tell this apart from a serious reaction related to a lack of blood flow to the heart, brain or other parts of the body. Get medical
help right away if you have any very serious side effects, including: chest pain, jaw/left arm pain, fainting, fast/irregular/pounding heartbeat,
vision changes, weakness on one side of the body, confusion, slurred speech, sudden or severe stomach/abdominal pain, bloody diarrhea, change in
the amount of urine.
Amerge (Naratriptan) may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are
also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get
medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe
nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.
A very serious allergic reaction to Amerge (Naratriptan) is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction,
including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Before taking Amerge (Naratriptan), tell your doctor or pharmacist if you are allergic to it; or to other triptan migraine drugs;
or it you have other allergies. Amerge (Naratriptan) may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to
your pharmacist for more details.
Before using Amerge (Naratriptan), tell your doctor or pharmacist your medical history, especially of: heart disease (e.g., chest pain, heart attack,
irregular heartbeat), decreased blood flow in the brain (e.g., stroke, transient ischemic attack), blood circulation disease (e.g., ischemic bowel
disease, Raynaud's disease), certain types of headaches (hemiplegic or basilar migraine), kidney disease, liver disease.
Tell your doctor if you have the following risk factors for heart disease: diabetes, family history of heart disease, high blood pressure, high
cholesterol, overweight, smoker, female after menopause, male over age 40.
If you are at high risk for heart disease, your doctor may want to check your heart before prescribing Amerge (Naratriptan).
Amerge (Naratriptan)g may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform
such activities safely. Limit alcoholic beverages.
The risk of heart disease and high blood pressure increases with age. Older adults may be more sensitive to the side effects of Amerge (Naratriptan), especially
increased blood pressure and heart problems.
Amerge (Naratriptan) should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.
It is not known whether Amerge (Naratriptan) passes into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects.
This website does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription
drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.
Other medications can affect the removal of Amerge (Naratriptan) from your body, which may affect how Amerge (Naratriptan) works. Examples include azole antifungals
such as ketoconazole/itraconazole, macrolide antibiotics such as erythromycin, protease inhibitors such as ritonavir.
The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotonin. Examples include street drugs such
as MDMA/"ecstasy," St. John's wort, certain antidepressants (including SSRIs such as fluoxetine/paroxetine, SNRIs such as duloxetine/venlafaxine),
among others. The risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs.
If you also take any ergotamine medication (e.g., dihydroergotamine or methysergide) or any other "triptan" drugs (e.g., zolmitriptan, sumatriptan),
you will need to separate your Amerge (Naratriptan) dose from your dose of these other medications in order to lessen the chance of serious side effects.
Ask you doctor how long you should wait between your doses of these drugs.
Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure
drugs (e.g., carbamazepine), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine),
psychiatric medicines (e.g., amitriptyline, chlorpromazine, risperidone, trazodone).
Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist
about the safe use of those products.
OVERDOSE: If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222.
NOTES: Do not share this medication with others.
Take Amerge (Naratriptan) only as needed when a migraine occurs, as directed by your doctor. Amerge (Naratriptan) should not be taken on a regular schedule.
Never increase your dose of Amerge (Naratriptan) or take it more often than prescribed by your doctor.
Certain foods/beverages or food additives (e.g., red wine, cheese, chocolate, monosodium glutamate) as well as some lifestyle patterns (e.g.,
irregular eating/sleeping habits, stress) may bring about a migraine headache. Avoiding these "triggers" may help decrease the frequency of
migraine headaches. Consult your doctor for more details.
Laboratory and/or medical tests (such as blood pressure) may be performed periodically to monitor your progress or check for side effects.
Consult your doctor for more details.
MISSED DOSE: Not applicable. (See How to Use section.)
STORAGE: Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.