AllopurinolZyloprim (Allopurinol) is used to treat chronic gout (gouty arthritis). This condition is thought to be caused by an excess of uric acid circulating in the blood. This medicine works by causing less uric acid to be produced by the body. Allopurinol will not relieve a gout attack that has already started. Also, it does not cure gout, but it will help prevent gout attacks. However, it works only after you have been taking it regularly for a few months. Allopurinol will help prevent gout attacks only as long as you continue to take it. Allopurinol may also be used to prevent certain kinds of kidney stones or other kidney problems.
Allopurinol Drug Info
Zyloprim is used to treat gout, high levels of uric acid in the body caused by certain cancer medications, and kidney stones. Allopurinol is in a class of medications called xanthine oxidase inhibitors. It works by reducing the production of uric acid in the body. High levels of uric acid may cause gout attacks or kidney stones. Allopurinol is used to prevent gout attacks, not to treat them once they occur.
How should I take Allopurinol?
Take Allopurinol exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
Take each dose with a full glass of water. Also, to reduce the risk of kidney stones forming, drink 8 to 10 full glasses (8-ounce glasses) of fluid daily, unless your doctor directs you to do otherwise.
Take allopurinol with food or milk to alleviate the potential for upset stomach.
Store allopurinol at room temperature away from heat and high moisture conditions.
Other uses for this medicine
Allopurinol is sometimes prescribed for the treatment of seizures, pain caused by pancreas disease, and certain infections. It is also sometimes used to improve survival after bypass surgery, to reduce ulcer relapses, and to prevent rejection of kidney transplants. Talk to your doctor about the possible risks of using this medication for your condition.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking Zyloprim,
What other medications should I try to avoid while consuming Allopurinol?
- report any medicinal allergies to your doctor or pharmacist.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: amoxicillin (Amoxil, Trimox); ampicillin (Polycillin, Principen); anticoagulants ('blood thinners') such as warfarin (Coumadin); cancer chemotherapy drugs such as cyclophosphamide (Cytoxan) and mercaptopurine (Purinethol); chlorpropamide (Diabinese); diuretics ('water pills'); medications that suppress the immune system such as azathioprine (Imuran) and cyclosporine (Neoral, Sandimmune); other medications for gout such as probenecid (Benemid) and sulfinpyrazone (Anturane); and tolbutamide (Orinase). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- inform your physician if you have had a disease of the kidney, liver or heart.
- tell your doctor if you are currently pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking allopurinol, call your physician to discuss your next step.
- you should know that allopurinol may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
- ask your doctor about the safe use of alcoholic beverages while you are taking allopurinol. Alcohol may decrease the effectiveness of allopurinol.
Use caution when driving, operating machinery, or performing other potentially hazardous activities. Allopurinol may cause drowsiness. If you experience drowsiness or an inability to stay awake, avoid these activities.
Avoid alcohol. It may worsen your condition.
Follow your doctor's recommendations about diet.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects may occur with this medication?
Allopurinol may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- upset stomach
Some side effects can be serious. The following symptoms are not common, but if you experience any of them, call your doctor immediately:
- skin rash
- painful urination
- blood in the urine
- irritation or redness of the eyes
- swelling of the lips or mouth
- fever, sore throat, chills, and other signs of infection
- loss of appetite
- unexpected weight loss
Zyloprim may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
What storage conditions are needed for Allopurinol?
Keep this medication in the specific container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
What other information should I know?
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to allopurinol.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.